Bangalore:
IISc Researchers have recently found in a study that surface modifications
made to the nanosheets of a certain two-diensiosional inorganic compound
can make them highly effective for delivering drugs to diseased cells.
The compound molybdenum disulfphied or 2DS2 is composed of molybdenum
and sulphur.
Researchers at the departent of organic chemistry and materials
research centre have also found that these chemically modified
nanosheets were also found to be safe to use inside living cells
.They modified the surface of 2D-MoS2 nanosheets with thoil
(sulpher containng) ligands. Thiolligands are certain componds
with an ability to bindthemselves to metal atoms.
"Our study shows that thiol exchange on 2D-MoS2
nanosheets is effective,and nano material is stable in the
presence of various biomolicules.This is an important
observation as it will make this nanomaterial highly benificial
for biomedical applications like drug delivery" explains
Marinmoy De,associate professor at the Department of organic
Chemistry and senior author of the study published in ACS Nano.
Source:
Times News Networks,TOI Bangalore.
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